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Similar content being viewed by others Acknowledgements This work was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (2020R1I1A3A04038150), Korea Basic Science Institute (National research Facilities and Equipment Center) grant funded by the Ministry of Education (2023R1A6C101A045), and the NRF grant funded by the Korea government (MSIT 2020R1A2C2103067)

[Abstract] Nature

The GCLC floxed mice (Cre-negative) shows lowered levels of glutathione in blood probably because introduced loxp sequences interrupt GCLC expression (Fig